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Antibodies

Recombinant Calnexin (Endoplasmic Reticulum Marker) Antibody

Product Sizes
100 ug
£671.00
821-RBM6-P1ABX-100UG
About this Product
SKU:
821-RBM6-P1ABX
Additional Names:
IP90 | Major histocompatibility complex class I antigen-binding protein p88 | p90
Application:
ELISA, Immunohistochemistry, Western Blot
translate.label.attr.clone:
CANX/9147R
Clonality:
Monoclonal
Extra Details:
It recognizes a protein of 90kDa; which is identified as Calnexin. Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum (ER) where they are often modified by the formation of disulfide bonds; amino-linked glycosylation and folding. To help proteins fold properly; the ER contains a pool of molecular chaperones including calnexin. It is a calcium-binding; endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins; facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.
Host:
Rabbit
Immunogen:
Recombinant N-terminal fragment of human Calnexin protein (around aa 1-300) (exact sequence is proprietary)
Isotype:
IgG
Molecular Weight:
90kDa
Research Area:
Cytokine Signaling; Immunology; Infectious Disease
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody