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Antibodies

ZNF408 / PRDM17 (Transcription Factor) Antibody

Product Sizes
100 ug
£671.00
79797-MSM1-P1-100UG
About this Product
SKU:
79797-MSM1-P1
Additional Names:
PR domain zinc finger protein 17
Application:
Flow Cytometry, Western Blot
translate.label.attr.clone:
PCRP-ZNF408-1E5
Clonality:
Monoclonal
Extra Details:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions; most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr ppel-type DNA binding domain and a KRAB domain; which is thought to interact with KAP1; thereby recruiting histone modifying proteins. As a member of the Kr ppel C2H2-type zinc-finger protein family; ZNF396 (zinc finger protein 396); also known as PRDM17 (PR domain zinc finger protein 17); is a 720 amino acid nuclear protein that contains ten C2H2-type zinc fingers. The gene encoding ZNF408 maps to human chromosome 11; which houses over 1;400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome; Jacobsen syndrome; Niemann-Pick disease; hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
Host:
Mouse
Immunogen:
Recombinant full-length human ZNF408 protein
Isotype:
IgG2b
Molecular Weight:
118kDa
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody