B7-H4 (Immuno-Inhibitory Protein) Antibody
Product Sizes
100 ug
£671.00
79679-MSM1-P1ABX-100UG
About this Product
- SKU:
- 79679-MSM1-P1ABX
- Additional Names:
- B7 homolog 4 | B7h.5 | Immune costimulatory protein B7-H4 | Protein B7S1 | T-cell costimulatory molecule B7x
- Application:
- ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- B7H4/1788
- Clonality:
- Monoclonal
- Extra Details:
- T cell activation and immune function are regulated by the innate immune system through positive and negative costimulatory proteins. One such protein; B7-H4 (B7-homolog 4); belongs to the B7 immunoglobulin superfamily of ligand-lymphocyte interacting proteins. Expressed primarily on the membrane of lymphoid cells; B7-H4 is an immuno-inhibitory protein that interacts with receptors on the surface of T lymphocytes; thus mediating cellular and humoral immune responses. Overexpression of the B7-H4 protein is associated with certain malignancies; including ovarian and breast cancer; as its interaction with T cells suppresses tumor-associated immunity. Current research suggests that; similar to Mucin 16 (CA-125); B7-H4 may be a useful biomarker for the early detection of ovarian cancer.
- Host:
- Mouse
- Immunogen:
- A recombinant fragment of human B7-H4 protein (exact sequence is proprietary)
- Isotype:
- IgG2a
- Molecular Weight:
- 35kDa
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=123182
