Recombinant PAX8 (Renal Cell Marker) Antibody
Product Sizes
20 ug
£364.00
7849-RBM8-P0-20UG
About this Product
- SKU:
- 7849-RBM8-P0
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- PAX8/3688R
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 62kDa; identified as PAX8. It is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis; thyroid follicular carcinomas; and atypical thyroid adenomas. PAX-8 is expressed in the thyroid (and associated carcinomas); non-ciliated mucosal cells of the fallopian tubes; and simple ovarian inclusion cysts; but not normal ovarian surface epithelial cells. PAX-8 is expressed in a high percentage of ovarian serous; endometrioid; and clear cell carcinomas; but only rarely in primary ovarian mucinous adenocarcinomas. PAX-8 expression is reported in renal tubules as well as renal cell carcinoma; nephroblastoma; and seminoma. PAX-8 antibody may be used as an additional immunohistochemical marker for renal epithelial tumors.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide corresponding to the C-terminus of human PAX8 protein
- Isotype:
- IgG
- Molecular Weight:
- 62kDa
- Research Area:
- Nuclear Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=123123
