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Antibodies

ZNF202 Antibody

Product Sizes
100 ug
£671.00
7753-MSM3-P1ABX-100UG
About this Product
SKU:
7753-MSM3-P1ABX
Additional Names:
Zinc finger protein with KRAB and SCAN domains 10
Application:
Flow Cytometry
translate.label.attr.clone:
PCRP-ZNF202-1C4
Clonality:
Monoclonal
Extra Details:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions; most of which encompass some form of transcriptional activation or repression. ZNF202 (zinc finger protein 202); also known as ZKSCAN10; is a 648 amino acid protein that contains eight C2H2-type zinc fingers; one KRAB domain and one SCAN box domain. Localized to the nucleus and expressed at high levels in the testis; ZNF202 belongs to the Kruppel C2H2-type zincfinger protein family and functions as a transcriptional repressor of genes that are involved in lipid metabolism. ZNF202 regulates the expression of several classes of proteins; including lipoprotein particles; transporters involved in lipid homeostasis; enzymes involved in lipid processing and a wide variety of proteins that are associated with energy metabolism. Defects in the gene encoding ZNF202 are associated with high cholesterol and may be involved in the pathogenesis of lung; ovarian and breast cancer. Two isoforms of ZNF202; designated a and b; exist due to alternative splicing events
Host:
Mouse
Immunogen:
Recombinant fragment (around 37-132) of human ZNF202 protein
Isotype:
IgG2a
Molecular Weight:
74.72kDa
Research Area:
Cardiovascular; Transcription Factors
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody