Proximal Nephrogenic Antigen (Carbonic Anhydrase IX) Antibody
Product Sizes
20 ug
£364.00
768-MSM3-P0-20UG
About this Product
- SKU:
- 768-MSM3-P0
- Additional Names:
- Carbonate dehydratase IX | Carbonic anhydrase IX | Membrane antigen MN | P54/58N | Renal cell carcinoma-associated antigen G250 | pMW1
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- PN-15
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a glycoprotein of ~200kDa; identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants; such as the Lewis blood group antigens; epithelial membrane antigen; HMFG; and AB blood group antigens. In normal kidney; gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule; as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly; gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.
- Host:
- Mouse
- Immunogen:
- Microsomal fraction of human renal cortical tissue homogenate
- Isotype:
- IgG2b
- Molecular Weight:
- 55kDa
- Research Area:
- Angiogenesis; Hypoxia
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=123067
