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Antibodies

Recombinant Carbonic Anhydrase VIII Antibody

Product Sizes
20 ug
£364.00
767-MSM7-P0-20UG
About this Product
SKU:
767-MSM7-P0
Additional Names:
Carbonic anhydrase VIII
Application:
Immunohistochemistry, Western Blot
translate.label.attr.clone:
rCA8/8835
Clonality:
Monoclonal
Extra Details:
The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However; the gene product lacks carbonic anhydrase activity (i.e.; the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in CA8 gene causes neuropathology; such as ataxia; mild mental retardation and the predisposition to quadrupedal gait. It is also associated with the development of colorectal and lung cancers. Additionally; it is upregulated in various cancers.
Host:
Mouse
Immunogen:
Recombinant full-length human CA8 protein
Isotype:
IgG1
Molecular Weight:
32.97kDa
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody