Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Antibodies

Recombinant 14-3-3E / Tryptophan 5-Monooxygenase Antibody

Product Sizes
100 ug
£671.00
7531-RBM3-P1-100UG
About this Product
SKU:
7531-RBM3-P1
Additional Names:
14-3-3E
Application:
Immunohistochemistry, Western Blot
translate.label.attr.clone:
YWHAE/8636R
Clonality:
Monoclonal
Extra Details:
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners; usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. It interacts with CDC25 phosphatases; RAF1 and IRS1 proteins; suggesting its role in diverse biochemical activities related to signal transduction; such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. The YWHAE gene which encodes 14-3-3E has also been identified as a possible susceptibility gene for schizophrenia.
Host:
Rabbit
Immunogen:
Recombinant human full-length YWHAE protein
Isotype:
IgG
Molecular Weight:
29.4kDa
Research Area:
AKT Signaling; Apoptosis; Autophagy; Cardiovascular; Defective Intrinsic Apoptosis; Infectious Disease; Signal Transduction; Transcription Factors
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody