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Antibodies

YY1 (Transcription Factor) Antibody

Product Sizes
100 ug
£671.00
7528-MSM3-P1-100UG
About this Product
SKU:
7528-MSM3-P1
Additional Names:
Delta transcription factor | INO80 complex subunit S | NF-E1 | Yin and yang 1
Application:
Immunohistochemistry, Western Blot
translate.label.attr.clone:
YY1/5436
Clonality:
Monoclonal
Extra Details:
The YY1 transcription factor; also known as NF-E1 (human) and Delta or UCRBP (mouse) is of interest due to its diverse effects on a wide variety of target genes. YY1 is broadly expressed in a wide range of cell types and contains four C-terminal zinc finger motifs of the Cys-Cys-His-His type and an unusual set of structural motifs at its N-terminal end. It binds to downstream elements in several vertebrate ribosomal protein genes; where it apparently acts positively to stimulate transcription and can act either negatively or positively in the context of the immunoglobulin k 3' enhancer and immunoglobulin heavy-chain ÔøΩE1 site as well as the P5 promoter of the adenoassociated virus. It thus appears that YY1 is a bifunctional protein; capable of functioning as an activator in some transcriptional control elements and a repressor in others.
Host:
Mouse
Immunogen:
His-tagged YY1 protein
Isotype:
IgG2
Molecular Weight:
40/68kDa
Research Area:
Apoptosis; Autophagy; Cardiovascular; Developmental Biology; Nuclear Marker; Signal Transduction; Transcription Factors
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody