Recombinant Wilm’s Tumor 1 (WT1) (Wilm’s Tumor & Mesothelial Marker) Antibody
Product Sizes
20 ug
£364.00
7490-MSM6-P0-20UG
About this Product
- SKU:
- 7490-MSM6-P0
- Additional Names:
- WT33
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- rWT1/857
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a 47-55kDa-tumor suppressor protein; identified as Wilm's Tumor (WT1) protein. The antibody reacts with all isoforms of the full-length WT1 and also identifies WT1 lacking exon 2-encoded amino acids; frequently found in subsets of sporadic Wilm's tumors.WT1; a sporadic and familial pediatric kidney tumor; is genetically heterogeneous. Wilm's tumor is associated with mutations of WT1; a zinc-finger transcription factor that is essential for the development of the metanephric kidney and the urogenital system. The WT1 gene is normally expressed in fetal kidney and mesothelium; and its expression has been suggested as a marker for Wilm's tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells; malignant mesothelioma; ovarian carcinoma; gonadoblastoma; nephroblastoma; and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human WT1 protein
- Isotype:
- IgG1
- Molecular Weight:
- 47-55kDa
- Research Area:
- Cancer; Cardiac Stem Cells; Developmental Biology; Stem Cell; Stem Cell Differentiation
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=122972
