Recombinant von Willebrand Factor/ Factor VIII Related-Ag (Endothelial Marker) Antibody
Product Sizes
20 ug
£364.00
7450-RBM17-P0-20UG
About this Product
- SKU:
- 7450-RBM17-P0
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- VWF/4384R
- Clonality:
- Monoclonal
- Extra Details:
- Human von Willebrand factor (VWFor factor VIII-related antigen) is a 309 kDa multimeric plasma glycoprotein; important in the maintenance of hemostasis; it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Von Willebrand factor also acts as a chaperone for coagulation factor VIII; delivering it to the site of injury; stabilizing its heterodimeric structure and protecting it from premature clearance from plasma. Von Willebrand factor is synthesized by endothelial cells and is reported to be expressed in a number of tumors of vascular origin. IHC results aid in the classification of acute myeloid leukemia FAB type M7; angiosarcoma and epithelioid hemangioendothelioma.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment (around aa 1150-1250) of human vWF protein (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 250kDa
- Research Area:
- Angiogenesis; Cardiovascular; Endothelial Cell Marker; Infectious Disease; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=122944
