Recombinant Vimentin (Mesenchymal Cell Marker) Antibody
Product Sizes
100 ug
£712.00
7431-RBM17-P1-100UG
About this Product
- SKU:
- 7431-RBM17-P1
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- MSVA-458R
- Clonality:
- Monoclonal
- Extra Details:
- This MAb reacts with a 58kDa protein identified as vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFP s) such as desmin; keratin; neurofilament; and glial fibrillary acid protein.Anti-vimentin alone is of limited value as a diagnostic tool; however; when used in panels with other antibodies; it is useful for the sub-classification of a given tumor. Expression of vimentin; when used in conjunction with anti-keratin; is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-vimentin. It labels a variety of mesenchymal cells; including melanocytes; lymphocytes; endothelial cells; and fibroblasts. Non-reactivity of anti-vimentin is often considered more useful than its positive reactivity; since there are a few tumors that do not contain vimentin; e.g. hepatoma and seminoma. Anti-vimentin is also useful as a tissue process control reagent.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment (around aa 2-466) of human Vimentin protein (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 57-60kDa
- Research Area:
- Cytokine Signaling; Immunology; Neural Stem Cells; Ovarian Cancer; Signal Transduction; Stem Cell Differentiation
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=147579
