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Antibodies

Recombinant VEGF (Vascular Endothelial Growth Factor) Antibody

Product Sizes
100 ug
£671.00
7422-RBM5-P1ABX-100UG
About this Product
SKU:
7422-RBM5-P1ABX
Additional Names:
Vascular permeability factor
Application:
Immunohistochemistry
translate.label.attr.clone:
VEGFA/7635R
Clonality:
Monoclonal
Extra Details:
This MAb recognizes proteins of 19-22kDa (reducing) and 38kDa-44kDa (non-reducing); identified as various isoforms of Vascular Endothelial Growth Factor or Vascular Permeability Factor (VEGF/VPF). It is highly specific to VEGF; which is a homodimeric; disulfide-linked glycoprotein with a close homology to platelet derived growth factor (PDGF). There are multiple isoforms of VEGF containing 206-; 189-; 165-; and 121-amino acid residues. The smaller two isoforms; VEGF165 and VEGF121; are secreted proteins and act as diffusible agents; whereas the larger two remain cell associated. VEGF/VPF plays an important role in angiogenesis; which promotes tumor progression and metastasis.
Host:
Rabbit
Immunogen:
Recombinant fragment (around aa1-200) of human VEGFA protein (exact sequence is proprietary)
Isotype:
IgG1
Molecular Weight:
19-22kDa (reducing) and 38kDa-44kDa (non-reducing)
Research Area:
BBB VCAM-1 Signaling; Bladder Cancer; Cardiovascular; Colon Cancer; Cytokine Signaling; Immunology; Infectious Disease; Neural Stem Cells; Signal Transduction; Stem Cell Differentiation; Transcription
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody