Recombinant Uroplakin II (UPK2) (Urothelial Differentiation Marker) Antibody
Product Sizes
100 ug
£671.00
7379-RBM3-P1-100UG
About this Product
- SKU:
- 7379-RBM3-P1
- Additional Names:
- Uroplakin II | UP2 | UPK2
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- UPK2/13348R
- Clonality:
- Monoclonal
- Extra Details:
- Uroplakin II (UPII) is a 15-kDa protein comprising urothelial plaques; which fortify the urothelial barrier. It is a highly specific marker for tumors of urothelial origin; particularly urothelial carcinoma (UC). UPII messenger RNA has been detected in the tissue and blood of UC patients. Immunohistochemistry utilizing UPII antibodies; such as UPK2/13669R; exhibits high specificity and increased sensitivity for urothelial carcinoma compared to UPIII antibodies. UPII immunohistochemistry is valuable for differentiating urothelial carcinoma from other malignancies; including prostate adenocarcinoma or metastatic breast carcinoma. It has also shown promise for detecting micrometastases of bladder cancer. UPII expression is found in various UC subtypes like micro-papillary; plasmacytoid; and sarcomatoid variants.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment (around aa 36-51) of human Uroplakin 2 (UPK2) protein (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 195kDa
- Research Area:
- Bladder Cancer; Cancer; Oncology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=149844
