Liver X Receptor beta (LXRB) (Orphan Receptor) Antibody

Product Sizes

100 ug

£671.00

7376-MSM1-P1-100UG

About this Product

SKU:: 7376-MSM1-P1
Additional Names:: Liver X receptor beta | Nuclear receptor NER | Nuclear receptor subfamily 1 group H member 2 | Ubiquitously-expressed nuclear receptor
Application:: ELISA
translate.label.attr.clone:: LXRB/2731
Clonality:: Monoclonal
Extra Details:: The liver X receptors; LXRA (NR1H3) and LXRB (NR1H2) form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function; controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver; adrenal gland; intestine; adipose tissue; macrophages; lung; and kidney; whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors and regulate expression of target genes containing LXR response elements. LXRB can inhibit proliferation and induce apoptosis of cancer cells.
Host:: Mouse
Immunogen:: Recombinant full-length human NR1H2 (LXRB) protein
Isotype:: IgG2c
Molecular Weight:: 56kDa
Research Area:: Cardiovascular; Nuclear Marker; Signal Transduction; Transcription Factors
Shipping Conditions:: Blue Ice
Storage Conditions:: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:: NeoBiotechnologies
Type:: Antibodies: Monoclonal Antibody

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