Liver X Receptor beta (LXRB) (Orphan Receptor) Antibody
Product Sizes
20 ug
£364.00
7376-MSM1-P0-20UG
About this Product
- SKU:
- 7376-MSM1-P0
- Additional Names:
- Liver X receptor beta | Nuclear receptor NER | Nuclear receptor subfamily 1 group H member 2 | Ubiquitously-expressed nuclear receptor
- Application:
- ELISA
- translate.label.attr.clone:
- LXRB/2731
- Clonality:
- Monoclonal
- Extra Details:
- The liver X receptors; LXRA (NR1H3) and LXRB (NR1H2) form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function; controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver; adrenal gland; intestine; adipose tissue; macrophages; lung; and kidney; whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors and regulate expression of target genes containing LXR response elements. LXRB can inhibit proliferation and induce apoptosis of cancer cells.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human NR1H2 (LXRB) protein
- Isotype:
- IgG2c
- Molecular Weight:
- 56kDa
- Research Area:
- Cardiovascular; Nuclear Marker; Signal Transduction; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=122734
