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Antibodies

SUMO-1 Antibody

Product Sizes
20 ug
£364.00
7341-MSM1X-P0-20UG
About this Product
SKU:
7341-MSM1X-P0
Additional Names:
GAP-modifying protein 1 | SMT3 homolog 3 | Sentrin | Ubiquitin-homology domain protein PIC1 | Ubiquitin-like protein SMT3C | Ubiquitin-like protein UBL1
Application:
Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
translate.label.attr.clone:
SPM571
Clonality:
Monoclonal
Extra Details:
This MAb is specific to SUMO-1 and shows no cross-reaction with either SUMO-2 or SUMO-3. The small ubiquitin-related modifier (SUMO) proteins; which include SUMO-1; SUMO-2 and SUMO-3; belong to the ubiquitin-like protein family. Like ubiquitin; the SUMO proteins are synthesized as precursor proteins that undergo processing before conjugation to target proteins. Also; both utilize the E1; E2; and E3 cascade enzymes for conjugation. However; SUMO and ubiquitin differ with respect to targeting. Ubiquitination predominantly targets proteins for degradation; whereas sumoylation targets proteins to a variety of cellular processing; including nuclear transport; transcriptional regulation; apoptosis and protein stability. The unconjugated SUMO-1 protein localizes to the nuclear membrane.
Host:
Mouse
Immunogen:
Recombinant human SUMO1 protein
Isotype:
IgG1
Molecular Weight:
11.5kDa (Monomer); 90kDa (Heteromer)
Research Area:
Cardiovascular; Cytokine Signaling; Immunology; Infectious Disease; Nuclear Marker; Transcription Factors
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody