UBE2B Antibody
Product Sizes
100 ug
£671.00
7320-MSM1-P1ABX-100UG
About this Product
- SKU:
- 7320-MSM1-P1ABX
- Additional Names:
- E2 ubiquitin-conjugating enzyme B | RAD6 homolog B | Ubiquitin carrier protein B | Ubiquitin-conjugating enzyme E2-17 kDa | Ubiquitin-protein ligase B
- Application:
- Flow Cytometry, Immunofluorescence
- translate.label.attr.clone:
- PCRP-UBE2B-1C7
- Clonality:
- Monoclonal
- Extra Details:
- The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. The first step requires the ATP-dependent activation of the Ub C-terminus and the assembly of multi-Ub chains by the Ub-activating enzyme known as the E1 component. The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex. The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate. UBE2A (ubiquitin-conjugating enzyme E2 A) and UBE2B (ubiquitin-conjugating enzyme E2 B) are both Ub-conjugating enzymes that are essential to post replication repair of UV-damaged DNA. UBE2A and UBE2B are both nuclear and cell membrane proteins that have been found to interact with Rad18.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human UBE2B protein
- Isotype:
- IgG2b
- Molecular Weight:
- 17kDa
- Research Area:
- Immunology; Nuclear Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=122671
