Recombinant Ubiquitin (Autophagy Marker) Antibody
Product Sizes
100 ug
£671.00
7314-MSM7-P1ABX-100UG
About this Product
- SKU:
- 7314-MSM7-P1ABX
- Additional Names:
- Ubiquitin B
- Application:
- Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- rUBB/9476
- Clonality:
- Monoclonal
- Extra Details:
- Ubiquitin is a highly conserved and plays an essential role in the ubiquitin-proteasome pathway. In ubiquitination process; it is first activated by forming a thiol-ester complex with the activation component E1; which is then transferred to ubiquitin-carrier protein E2; followed by to ubiquitin ligase E3 for final delivery to epsilon-NH2 of the target protein lysine residue. IkB; p53; cdc25A; Bcl-2 etc. are shown as targets of ubiquitin-proteasome process as part of regulation of cell cycle progression; differentiation; cell stress response; and apoptosis. Moreover; ubiquitin have been reported to bind covalently with pathological inclusions which are resistant to degradation e.g. neurofibrillary tangles/paired helical filaments in Alzheimer's disease; Lewy bodies seen in Parkinson's disease; and Pick bodies found in Pick's disease etc.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human Ubiquitin protein (around aa 1-119) (exact sequence is proprietary)
- Isotype:
- IgG2b
- Molecular Weight:
- 9kDa
- Research Area:
- Apoptosis; Autophagy; Cardiovascular; Cytokine Signaling; Developmental Biology; Hypoxia; Immunology; Infectious Disease; Neuroscience; Ovarian Cancer; Signal Transduction; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=141138
