Recombinant Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker) Antibody
Product Sizes
20 ug
£364.00
7306-RBM8-P0-20UG
About this Product
- SKU:
- 7306-RBM8-P0
- Additional Names:
- Catalase B | Glycoprotein 75 | Melanoma antigen gp75 | Tyrosinase-related protein 1
- Application:
- ELISA, Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- TYRP1/2340R
- Clonality:
- Monoclonal
- Extra Details:
- It reacts with a 75kDa melanocyte-specific gene product; identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma; normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment (around aa 257-377) of human TYRP1 protein (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 75kDa
- Research Area:
- Cardiovascular
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=122643
