OX40 / CD134 / TNFRSF4 (Immuno-Oncology Target) Antibody
Product Sizes
100 ug
£671.00
7293-MSM8-P1-100UG
About this Product
- SKU:
- 7293-MSM8-P1
- Additional Names:
- ACT35 antigen | OX40L receptor | TAX transcriptionally-activated glycoprotein 1 receptor
- Application:
- ELISA
- translate.label.attr.clone:
- OX40/3428
- Clonality:
- Monoclonal
- Extra Details:
- This MAb recognizes a protein of 43kDa; identified as OX40; which is also known as CD134. OX40 is a type I integral membrane glycoprotein and member of the tumor necrosis factor/nerve growth factor receptor (TNFR/NGFR) family. It is expressed on activated T lymphocytes; hematopoietic precursor cells and fibroblasts. It functions as a T cell co-stimulatory receptor when bound by OX40 Ligand / TNFSF4 that is expressed by antigen presenting cells. OX40 thereby plays roles in T-cell activation as well as the regulation of differentiation; proliferation or apoptosis of normal and malignant lymphoid cells. OX40 is upregulated at the sites of inflammation; especially in case of multiple sclerosis and psoriatic lesions.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human OX40 (CD134) protein (around aa 59-205) (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 43kDa
- Research Area:
- AKT Signaling; Cardiovascular; Cytokine Signaling; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=122525
