Recombinant TSH-Receptor; B-Chain (Thyroid Marker) Antibody
Product Sizes
20 ug
£364.00
7253-RBM7-P0-20UG
About this Product
- SKU:
- 7253-RBM7-P0
- Additional Names:
- Thyroid-stimulating hormone receptor
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- TSHRB/1607R
- Clonality:
- Monoclonal
- Extra Details:
- Thyroid-stimulating hormone (TSH; also known as thyrotropin) is a glycoprotein involved in the control of thyroid structure and metabolism; which stimulates the release of the thyroid hormones. TSH is regulated by thyroid hormone (T3) and various retinoid compounds. TSH binds to the thyroid-stimulating hormone receptor (TSHR); which is cleaved into two subunits; A and B; and plays a major role in regulating thyroid function. The third cytoplasmic loop of TSHR has been identified as critical for its role in regulating inositol phosphate and cAMP formation. In Grave s disease; an autoimmune disorder; TSHR is activated by autoantibodies; which may be stimulated by the cleavage of the A and B subunits.
- Host:
- Rabbit
- Immunogen:
- Recombinant human TSHR; B-Chain protein
- Isotype:
- IgG
- Molecular Weight:
- 42kDa
- Research Area:
- Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=131965
