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Antibodies

Recombinant Thyroid Stimulating Hormone; beta (TSH beta) (Pituitary Marker) Antibody

Product Sizes
20 ug
£364.00
7252-RBM3-P0-20UG
About this Product
SKU:
7252-RBM3-P0
Additional Names:
Thyroid-stimulating hormone subunit beta | Thyrotropin beta chain
Application:
Immunohistochemistry
translate.label.attr.clone:
TSHb/7001R
Clonality:
Monoclonal
Extra Details:
The four human glycoprotein hormones chorionic gonadotropin (CG); luteinizing hormone (LH); follicle stimulating hormone (FSH); and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated non-covalently. The alpha subunits of these hormones are identical; however; their beta chains are unique and confer biological specificity. TSH is synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland. TSH stimulates the thyroid gland to secrete the hormones thyroxine (T4) and triiodothyronine (T3). TSH production is controlled by a Thyrotropin-Releasing Hormone (TRH); which is manufactured in the hypothalamus and transported to the pituitary gland; where it increases TSH production and release. Somatostatin is also produced by the hypothalamus and has an opposite effect on the pituitary production of TSH; decreasing or inhibiting its release. TSH is a useful marker in classification of pituitary tumors and the study of pituitary disease.
Host:
Rabbit
Immunogen:
Recombinant human TSH beta fragment
Isotype:
IgG
Molecular Weight:
16kDa
Research Area:
Cardiovascular; Signal Transduction
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. ;Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody