Recombinant Topoisomerase II alpha (Proliferation & Drug-Resistance Marker) Antibody
Product Sizes
100 ug
£671.00
7153-MSM6-P1ABX-100UG
About this Product
- SKU:
- 7153-MSM6-P1ABX
- Additional Names:
- DNA topoisomerase II; alpha isozyme
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- rTOP2A/6629
- Clonality:
- Monoclonal
- Extra Details:
- It recognizes a 170kDa protein; which is identified as topoisomerase II伪. It shows no cross-reaction with Topoisomerase II 尾 or I. Topo II 伪 plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-; G2- & M-phases in transformed and developmentally regulated normal cells. Topo II 伪 is also implicated in drug resistance of tumor cells and has been shown to be over-expressed in many human cancers. Decreased expression of Topo IIa is the predominant mechanism of resistance to several chemotherapeutic agents.
- Host:
- Mouse
- Immunogen:
- Recombinant human Topoisomerase II alpha fragment (aa1352-1493)
- Isotype:
- IgG1
- Molecular Weight:
- 170kDa
- Research Area:
- Nuclear Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=122255
