Recombinant TNF-alpha (Tumor Necrosis Factor alpha) Antibody
Product Sizes
100 ug
£671.00
7124-RBM13-P1-100UG
About this Product
- SKU:
- 7124-RBM13-P1
- Additional Names:
- Cachectin | TNF-alpha | Tumor necrosis factor ligand superfamily member 2
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- TNF/1500R
- Clonality:
- Monoclonal
- Extra Details:
- This MAb recognizes human 17-26kDa protein; which is identified as cytokine TNF-alpha (Tumor Necrosis Factor-alpha). TNF-alpha can be expressed as a 17kDa free molecule; or as a 26kDa membrane protein. TNF-alpha is a protein secreted by lipopolysaccharide-stimulated macrophages; and causes tumor necrosis when injected into tumor bearing mice. TNF alpha causes cytolysis of certain transformed cells; being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells; TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines; activating polymorphonuclear neutrophils and osteoclasts; and induction of interleukin 1; prostaglandin E2 and collagenase production. TNF alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex.
- Host:
- Rabbit
- Immunogen:
- Recombinant full-length human TNF-alpha protein
- Isotype:
- IgG
- Molecular Weight:
- 17kDa
- Research Area:
- AKT Signaling; Apoptosis; Autophagy; Cardiovascular; Colon Cancer; Cytokine Signaling; Developmental Biology; Hematopoietic Stem Cells; Immunology; MAPK Signaling; Neuroinflammation; Ovarian Cancer; S
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=122222
