TMPRSS2 (Transmembrane Serine Protease 2) Antibody
Product Sizes
100 ug
£671.00
7113-MSM1-P1ABX-100UG
About this Product
- SKU:
- 7113-MSM1-P1ABX
- Additional Names:
- Serine protease 10
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- TMPRSS2/7410
- Clonality:
- Monoclonal
- Extra Details:
- Extracellular proteases mediate the digestion of neighboring extracellular matrix components in initial tumor growth; allow desquamation of tumor cells into the surrounding environment; provide the basis for invasion of basement membranes in targeted metastatic organs and are required for release and activation of many growth and angiogenic factors. The TMPRSS2 gene encodes a 492 amino acid multimeric serine protease; which is mainly expressed in the mouse prostate and kidney; and is also expressed in the human small intestine; prostate; colon; stomach and salivary gland. TMPRSS2 contains several domains; including a serine protease domain of the S1 family; a scavenger receptor cysteine-rich domain of group A; an LDL receptor class A domain and a transmembrane domain. TMPRSS2 is expressed as a full length form and a cleaved protease domain and its expression is increased by androgenic hormones. TMPRSS2 is also expressed in prostate carcinoma; suggesting that it may play a role in prostate carcinogenesis.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human TMPRSS2 protein
- Isotype:
- IgG2b
- Molecular Weight:
- 70kDa
- Research Area:
- Infectious Disease
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=132453
