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Antibodies

Recombinant CD284 (Toll-Like Receptor 4) Antibody

Product Sizes
100 ug
£671.00
7099-RBM2-P1ABX-100UG
About this Product
SKU:
7099-RBM2-P1ABX
Additional Names:
hToll
Application:
ELISA
translate.label.attr.clone:
TLR4/3895R
Clonality:
Monoclonal
Extra Details:
This MAb reacts with human Toll-like receptor 2 (TLR4). It is a member of the Toll-like receptor (TLR) family; which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents; and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene.
Host:
Rabbit
Immunogen:
Recombinant full-length human TLR4 protein
Isotype:
IgG
Molecular Weight:
95-120kDa
Research Area:
Cardiovascular; Colon Cancer; Immunology; Infectious Disease
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody