Recombinant TTF-1 / NKX2.1 (Thyroid & Lung Epithelial Marker) Antibody
Product Sizes
100 ug
£671.00
7080-RBM12-P1ABX-100UG
About this Product
- SKU:
- 7080-RBM12-P1ABX
- Additional Names:
- Homeobox protein NK-2 homolog A | Thyroid nuclear factor 1 | Thyroid transcription factor 1 | Thyroid-specific enhancer-binding protein
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- TTF1/8123R
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of 40kDa; identified as Thyroid transcription factor-1 (TTF-1). TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver; stomach; pancreas; small intestine; colon; kidney; breast; skin; testes; pituitary; prostate; and adrenal glands are unreactive. Anti-TTF-1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast; mediastinal germ cell tumors; and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates.Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 reactivity is also seen in thyroid malignancies.
- Host:
- Rabbit
- Immunogen:
- Recombinant full-length human NXK2-1 (TTF-1) protein
- Isotype:
- IgG
- Molecular Weight:
- 40kDa
- Research Area:
- Neuroscience
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=130460
