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Antibodies

TIMP-3 (Tissue Inhibitor of Metalloproteinase-3) Antibody

Product Sizes
20 ug
£364.00
7078-RBP1-P0-20UG
About this Product
SKU:
7078-RBP1-P0
Additional Names:
Protein MIG-5 | Tissue inhibitor of metalloproteinases 3
Application:
Flow Cytometry, Immunofluorescence, Immunohistochemistry
Clonality:
Polyclonal
Extra Details:
TIMP3 (tissue inhibitor of metalloproteinases 3); along with family members TIMP1; TIMP2; and TIMP4; are inhibitors of the matrix metalloproteinases (MMPs); a group of peptidases involved in degradation of the extracellular matrix (ECM). An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP's inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia; and in the formation; branching and expansion of epithelial tubes.
Host:
Rabbit
Immunogen:
The amino acid sequence (aa175-211); used as the immunogen for TIMP3 Ab; is 100% homologous in human; cow; dog and horse; and 94% homologous in Mouse and rat.
Isotype:
IgG
Molecular Weight:
30kDa
Research Area:
AKT Signaling; Angiogenesis; Cardiovascular; Endothelial Cell Marker
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Polyclonal Antibody