TIMP1 (Marker of Lymph Node Metastasis) Antibody
Product Sizes
20 ug
£364.00
7076-MSM8-P0-20UG
About this Product
- SKU:
- 7076-MSM8-P0
- Additional Names:
- Erythroid-potentiating activity | Fibroblast collagenase inhibitor | Tissue inhibitor of metalloproteinases 1
- Application:
- ELISA, Immunohistochemistry
- translate.label.attr.clone:
- TIMP1/4358
- Clonality:
- Monoclonal
- Extra Details:
- TIMP-1; TIMP-2; TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases -1; -2; -3 and -4) complex with metalloproteinases such as collagenases; gelatinases and stromelysins; resulting in irreversible inactivation of the metalloproteinase. TIMP-1 is identical to EPA (erythroid-potentiation activity). PTH has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia; and in the formation; branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart tissues. Studies have demonstrated that TIMP1 is useful as a biomarker for early detection of colorectal cancer; outperforming CEA. Additionally; TIMP1 studies have demonstrated its role in CRC tumorigenesis; as well as observing its overexpression in metastatic lymph nodes.
- Host:
- Mouse
- Immunogen:
- Recombinant human TIMP1 protein fragment (around aa 1-200) (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 23kDa
- Research Area:
- AKT Signaling; Angiogenesis; Cardiovascular; Cytokine Signaling; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=127337
