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Antibodies

Recombinant Thrombomodulin / CD141 (Endothelial Cell Marker) Antibody

Product Sizes
20 ug
£364.00
7056-MSM3-P0-20UG
About this Product
SKU:
7056-MSM3-P0
Additional Names:
Fetomodulin
Application:
ELISA, Immunohistochemistry
translate.label.attr.clone:
rTHBD/1591
Clonality:
Monoclonal
Extra Details:
It recognizes a protein of 75kDa; identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells; such as endothelial and mesothelial cells. In addition; synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi's sarcoma; angiosarcoma; and epithelioid hemangioendothelioma). Hence; anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently; thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.
Host:
Mouse
Immunogen:
Recombinant fragment (around aa 69-194) of human Thrombomodulin (CD141) protein (exact sequence is proprietary)
Isotype:
IgG1
Molecular Weight:
100kDa
Research Area:
Cardiovascular; Endothelial Cell Marker
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody