Recombinant Transglutaminase II (TGM2) (FN Binding Domain) Antibody
Product Sizes
20 ug
£364.00
7052-RBM3-P0-20UG
About this Product
- SKU:
- 7052-RBM3-P0
- Additional Names:
- Erythrocyte transglutaminase | Heart G alpha(h) | Isopeptidase TGM2 | Protein G alpha(h) | Protein-glutamine deamidase TGM2 | Protein-glutamine dopaminyltransferase TGM2 | Protein-glutamine histaminyltransferase TGM2 | Protein-glutamine noradrenalinyltransferase TGM2 | Protein-glutamine serotonyltransferase TGM2 | Tissue transglutaminase | Transglutaminase C | Transglutaminase H | Transglutaminase II | Transglutaminase-2
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- TGM2/6943R
- Clonality:
- Monoclonal
- Extra Details:
- Tissue transglutaminase (tTG) is a 75 kDa monomeric globular protein expressed in the majority of cells and tissues. tTG localizes mainly in the cytoplasm but some tGT is present on the cell surface and is association with the extracellular matrix. In addition to its guanosine triphosphatase (GTPase) activity; tTG catalyzes the posttranslational modification of proteins by transamidation of available glutamine residues. Extracellular tTG is able to bind to and cross-link several ECM proteins and may function to stabilize the ECM and basement membranes. The protein is translated as a fully active enzyme and there is no evidence for proteolytic activation. High constitutive expression and accumulation of active tTG is observed in (among others) endothelial cells; platelets; vascular smooth muscle cells and epithelial cells of the lens. tTG is expressed at very low levels in skeletal muscle cells and neurons and may be difficult to detect in these cell/tissue types.
- Host:
- Rabbit
- Immunogen:
- Recombinant full-length human TGM2 protein
- Isotype:
- IgG
- Molecular Weight:
- 77-85kDa
- Research Area:
- Cardiovascular
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=122016
