Recombinant Transforming Growth Factor Beta Receptor 1 (TGFBR1) Antibody
Product Sizes
100 ug
£671.00
7046-MSM3-P1ABX-100UG
About this Product
- SKU:
- 7046-MSM3-P1ABX
- Additional Names:
- Activin A receptor type II-like protein kinase of 53kD | Activin receptor-like kinase 5 (ALK-5; ALK5) | Serine/threonine-protein kinase receptor R4 (SKR4) | TGF-beta type I receptor | Transforming growth factor-beta receptor type I (TGF-beta receptor type I; TbetaR-I)
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- rG3E6
- Clonality:
- Monoclonal
- Extra Details:
- Transforming growth factor beta (TGFB) inhibits cell proliferation and stimulates cell differentiation. This is achieved through a receptor complex of types I and II TGFB receptors. The type II receptor is a transmembrane serine/threonine kinase which is able to bind TGFB and transactivate the type I receptor. TGFB receptors are found in all myometrial tissues and; in the kidney; they are found exclusively in renal tubular cells. In normal gastric mucosa; type I and II receptors are demonstrated in fundic glands; but not on surface mucous cells and in normal small bowel and colon; TGFB receptors are expressed in the epithelial cells of the upper crypts.
- Host:
- Mouse
- Immunogen:
- Prokaryotic recombinant protein corresponding to the external domain of the human transforming growth factor beta receptor type 1 molecule
- Isotype:
- IgM
- Molecular Weight:
- 53kDa
- Research Area:
- AKT Signaling; Angiogenesis; Apoptosis; Breast Cancer; Cancer; Colorectal Cancer; Cytokine Signaling
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=146499
