TGF-beta (Transforming Growth Factor beta) Antibody
Product Sizes
20 ug
£364.00
7040-MSM4-P0-20UG
About this Product
- SKU:
- 7040-MSM4-P0
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- TGFB/7240
- Clonality:
- Monoclonal
- Extra Details:
- This MAb recognizes TGF beta 1; 2 and 3. Three TGFβs have been identified in mammals. TGFβ1; TGFβ2 and TGFβ3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFβ requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall; the mature region of the TGFβ3 protein has approximately 80% identity to the mature region of both TGFβ1 and TGFβ2. However; the NH2 terminals or precursor regions of their molecules share only 27% sequence identity. TGFβ s inhibits the growth of epithelial cells and stimulate the growth of mesenchymal cells. �
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa200-390) of human TGFB protein
- Isotype:
- IgG2
- Molecular Weight:
- 13kDa
- Research Area:
- AKT Signaling; Angiogenesis; Cardiovascular; Colon Cancer; Complement System; Cytokine Signaling; Developmental Biology; Immunology; Infectious Disease; MAPK Signaling; Mesenchymal Stem Cell Different
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=131935
