MLX Antibody
Product Sizes
100 ug
£671.00
6945-MSM1-P1-100UG
About this Product
- SKU:
- 6945-MSM1-P1
- Additional Names:
- Class D basic helix-loop-helix protein 13 | Max-like bHLHZip protein | Protein BigMax | Transcription factor-like protein 4
- Application:
- Flow Cytometry, Immunofluorescence, Western Blot
- translate.label.attr.clone:
- PCRP-MLX-1G8
- Clonality:
- Monoclonal
- Extra Details:
- Max is a nuclear localized bHLH-Zip protein that forms homodimers or heterodimers with Myc family members; including Myc; Mad1; Mad3; Mad4; Mxi1 and Mnt (or Rox). These dimers bind to the E-box sequence CACGTG in order to regulate cell growth; proliferation and apoptosis. Mlx (Max-like protein X) is a bHLH-Zip protein that is structurally and functionally related to Max. Like Max; Mlx is broadly expressed in many tissues and has a long half-life. Mlx also forms homodimers or heterodimers with members of the Myc family; specifically Mad1; Mad4 and Rox; and members of the Mondo family; to repress or activate transcription from CACGTG E-boxes. MondoA forms weak homodimers and preferentially forms heterodimers with Mlx. The MondoA/Mlx complex is primarily localized to the cytoplasm; but will translocate to the nucleus in response to leptomycin B. Mlx can also dimerize with WBSCR14; a protein involved in Williams-Beuren syndrome (WBS); to repress E-box transcription; which provides further evidence that Mlx is a critical element in a transcription factor network.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human MLX protein
- Isotype:
- IgG2b
- Molecular Weight:
- 30kDa
- Research Area:
- Apoptosis; Autophagy; Nuclear Marker
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=121833
