Tal1 Antibody
Product Sizes
100 ug
£671.00
6886-MSM3-P1-100UG
About this Product
- SKU:
- 6886-MSM3-P1
- Additional Names:
- Class A basic helix-loop-helix protein 17 | Stem cell protein | T-cell leukemia/lymphoma protein 5
- Application:
- ELISA
- translate.label.attr.clone:
- TAL1/3146
- Clonality:
- Monoclonal
- Extra Details:
- Activation of TAL1 characterizes up to 60% of cases of human T cell acute lymphoblastic leukemia; making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box. In addition; leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase II; a serine/threonine protein kinase known to modulate the activity of other HLH transcription factors.
- Host:
- Mouse
- Immunogen:
- Recombinant human full-length TAL1 protein
- Isotype:
- IgG1
- Molecular Weight:
- 42kDa
- Research Area:
- Cardiovascular; Developmental Biology; Nuclear Marker; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=121806
