Recombinant TBXT / T-box transcription factor T / Brachyury Antibody
Product Sizes
20 ug
£364.00
6862-RBM3-P0-20UG
About this Product
- SKU:
- 6862-RBM3-P0
- Additional Names:
- Brachyury protein | Protein T
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- TBXT/7853R
- Clonality:
- Monoclonal
- Extra Details:
- The T-box gene family consists of members that share a unique DNA binding domain. The best characterized T-box (Tbx) gene; brachyury or T; encodes a transcription factor that plays an important role in early vertebrate development. Tbx genes are a family of developmental regulators with more than 20 members recently identified among invertebrates and vertebrates. Mutations in Tbx genes have been found to cause several human diseases. The understanding of functional mechanisms of Tbx products has come mainly from the prototypical T/brachyury protein; which is a transcription activator. The T-domain is a highly conserved DNA-binding motif originally defined in brachyury and characteristic of the Tbx family of transcription factors. The murine brachyury (T) gene is required in posterior mesoderm formation and axial development. Mutant embryos lacking T gene function are deficient in notochord differentiation and posterior mesoderm formation; but develop anterior mesoderm.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment (around aa 235-435) of human TBXT protein (exact sequence is proprietary)
- Isotype:
- IgG
- Molecular Weight:
- 47kDa
- Research Area:
- Cardiovascular; Developmental Biology; Nuclear Marker; Stem Cell Differentiation
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=128944
