Serum Response Element Binding Transcription Factor (SRF) Antibody
Product Sizes
100 ug
£671.00
6722-MSM1-P1ABX-100UG
About this Product
- SKU:
- 6722-MSM1-P1ABX
- Application:
- ELISA, Flow Cytometry, Immunofluorescence, Western Blot
- translate.label.attr.clone:
- PCRP-SRF-1F1
- Clonality:
- Monoclonal
- Extra Details:
- Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE); a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF-binding sites are also constitutive promotor elements in many muscle-specific promotors. At the c-Fos SRE; formation of a ternary complex containing SRF and its accessory protein p62TCF appears to be important for signal transduction. Two related Ets domain proteins; Elk-1 and SRF accessory protein-1 (SAP-1); have DNA binding properties identical to that of p62TCF. Elk-1 and SAP-1 contain two homologous regions of which the two amino-terminal regions; the Ets domain (box A) and the B box; mediate ternary complex formation with SRF. The third homologous region; the C box located toward the C-terminus of the proteins; contains conserved consensus phosphorylation sites for MAP kinases.
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human SRF protein
- Isotype:
- IgG1
- Molecular Weight:
- 40-67kDa
- Research Area:
- Cardiovascular; Developmental Biology; MAPK Signaling; Nuclear Marker; Signal Transduction; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=121686
