Spectrin beta I (SPTB) Antibody
Product Sizes
20 ug
£364.00
6710-MSM1-P0-20UG
About this Product
- SKU:
- 6710-MSM1-P0
- Additional Names:
- Beta-III spectrin | Spinocerebellar ataxia 5 protein
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- RG/26
- Clonality:
- Monoclonal
- Extra Details:
- Spectrin is a cytoskeletal protein that lines the intracellular side of the plasma membrane of many cell types in pentagonal or hexagonal arrangements; forming a scaffolding and playing an important role in maintenance of plasma membrane integrity and cytoskeletal structure. In certain types of brain injury such as diffuse axonal injury; spectrin is irreversibly cleaved by the proteolytic enzyme calpain; destroying the cytosketelon. Spectrin cleavage causes the membrane to form blebs and ultimately to be degraded; usually leading to cell death.
- Host:
- Mouse
- Immunogen:
- Red cell membranes
- Isotype:
- IgG2a
- Molecular Weight:
- 246kDa
- Research Area:
- Developmental Biology; Signal Transduction
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=121624
