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Antibodies

Recombinant CD43 (T-Cell Marker) Antibody

Product Sizes
20 ug
£364.00
6693-RBM6-P0-20UG
About this Product
SKU:
6693-RBM6-P0
Additional Names:
GPL115 | Galactoglycoprotein | Leukocyte sialoglycoprotein | Sialophorin
Application:
Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
translate.label.attr.clone:
SPN/1766R
Clonality:
Monoclonal
Extra Details:
It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation); identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma; especially a low-grade lymphoma; rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20; effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.
Host:
Rabbit
Immunogen:
Recombinant full-length human SPN protein
Isotype:
IgG
Molecular Weight:
115|95|or 135kDa
Research Area:
B Cell Markers; Cardiovascular; Hematopoietic Stem Cells
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody