Recombinant PU.1 (SPI-1) (B-Cell Marker) Antibody
Product Sizes
20 ug
£364.00
6688-MSM3-P0-20UG
About this Product
- SKU:
- 6688-MSM3-P0
- Additional Names:
- 31 kDa-transforming protein
- Application:
- Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- rPU1/2146
- Clonality:
- Monoclonal
- Extra Details:
- PU.1 is a member of the ETS family of transcription factors and is important for normal B-cell development. It is expressed in the myeloid lineage and in immature as well as mature B-lymphocytes; with the exception of plasma cells. PU.1 is expressed in germinal center B-cells and mantle B-cells. Various lymphomas are also positive for this marker. It is essential during early B-cell differentiation. The absence of PU.1 results in total block of B-cell development at the pre-pro stage. PU.1 plays a key role in normal myeloid differentiation; and regulates the expression of immunoglobulin and other genes that are important for B-cell development.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (around aa 16-170) of human PU.1 protein (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 40kDa
- Research Area:
- Developmental Biology; Nuclear Marker; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=121531
