Recombinant SOX11 (Mantle Cell Lymphoma Marker) Antibody
Product Sizes
100 ug
£671.00
6664-RBM5-P1ABX-100UG
About this Product
- SKU:
- 6664-RBM5-P1ABX
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- SOX11/3235R
- Clonality:
- Monoclonal
- Extra Details:
- Recognizes a protein of ~47kDa; identified as SOX11. This MAb is highly specific and does not cross-react with other members of the SOX-family. Mantle cell lymphoma (MCL) accounts for 5% to 10% of mature B-cell neoplasms and is an aggressive disease genetically characterized by overexpression of Cyclin D1. Cyclin D1 overexpression is the hallmark of MCL. However; approximately 5%-10% of MCLs lack Cyclin D1 expression and may be misdiagnosed. Almost all Cyclin D1-positive as well as Cyclin D1-negative MCL; show overexpression of SOX-11. The detection of this transcription factor is a useful biomarker for identifying true cyclin D1-negative MCL.
- Host:
- Rabbit
- Immunogen:
- Recombinant fragment (around aa300-400) of human SOX11 protein
- Isotype:
- IgG
- Molecular Weight:
- 47kDa
- Research Area:
- Cardiovascular
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=121474
