Recombinant SOX2 (Embryonic Stem Cell Marker) Antibody

Product Sizes

100 ug

£671.00

6657-RBM6-P1ABX-100UG

About this Product

SKU:: 6657-RBM6-P1ABX
Application:: ELISA, Immunohistochemistry, Western Blot
translate.label.attr.clone:: SOX2/3811R
Clonality:: Monoclonal
Extra Details:: SOX2 is required for stem cell maintenance in the central nervous system; and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Reportedly; SOX2 is associated with aggressive phenotypes of breast; head and neck; gastric; colorectal; bladder; and small cell lung cancers. However; SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker.
Host:: Rabbit
Immunogen:: Recombinant fragment (within aa176-305) of human SOX2 protein (exact sequence is proprietary)
Isotype:: IgG
Molecular Weight:: 34kDa
Research Area:: Cytokine Signaling; Developmental Biology; Immunology; Neural Stem Cells; Signal Transduction; Stem Cell Differentiation; Transcription Factors
Shipping Conditions:: Blue Ice
Storage Conditions:: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:: NeoBiotechnologies
Type:: Antibodies: Monoclonal Antibody

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