Recombinant SOX2 (Embryonic Stem Cell Marker) Antibody
Product Sizes
20 ug
£364.00
6657-MSM5-P0-20UG
About this Product
- SKU:
- 6657-MSM5-P0
- Application:
- ELISA, Immunohistochemistry, Western Blot
- translate.label.attr.clone:
- rSOX2/1792
- Clonality:
- Monoclonal
- Extra Details:
- SOX2 is required for stem cell maintenance in the central nervous system; and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Reportedly; SOX2 is associated with aggressive phenotypes of breast; head and neck; gastric; colorectal; bladder; and small cell lung cancers. However; SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment (within aa176-305) of human SOX2 protein (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 34kDa
- Research Area:
- Cytokine Signaling; Developmental Biology; Immunology; Neural Stem Cells; Signal Transduction; Stem Cell Differentiation; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=121384
