SNAPC4 Antibody
Product Sizes
100 ug
£671.00
6621-MSM2-P1ABX-100UG
About this Product
- SKU:
- 6621-MSM2-P1ABX
- Additional Names:
- Proximal sequence element-binding transcription factor subunit alpha | snRNA-activating protein complex 190 kDa subunit
- Application:
- Flow Cytometry, Immunohistochemistry
- translate.label.attr.clone:
- PCRP-SNAPC4-3A7
- Clonality:
- Monoclonal
- Extra Details:
- TATA-box binding protein (TBP) interactions with TBP-associated factors (TAFs) are required for the transcription of RNA polymerases. One particular TBP-TAF complex; snRNA-activating protein complex (SNAPC); is unusual in that it regulates basal transcription of both RNA polymerase II and III by binding specifically to a non-TATA-box proximal sequence element (PSE). SNAPC consists of five subunits of varying size. SNAPC binds to Oct-1 and TBP; which are activators of snRNA and RNA polymerases; respectively. The POU domain of Oct-1 binds to SNAPC 190 and effectively recruits SNAPC to the PSE. The cooperative binding of SNAPC and Oct-1 to their respective sequence elements is mediated by a nucleosome positioned between the two sequence elements. SNAPC 19 mediates the assembly of the subunits to form a functional SNAPC transcription regulator. SNAPC 50 (also designated PTFβ) contains two zinc finger motifs and binds to SNAPC 43 (also designated PTFÎ �) but not SNAPC 45 (PTFÎ �).
- Host:
- Mouse
- Immunogen:
- Recombinant full-length human SNAPC4 protein
- Isotype:
- IgG2b
- Molecular Weight:
- 200kDa
- Research Area:
- Nuclear Marker; Transcription Factors
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=131869
