Band III Antibody
Product Sizes
100 ug
£671.00
6521-MSM1-P1ABX-100UG
About this Product
- SKU:
- 6521-MSM1-P1ABX
- Additional Names:
- Anion exchange protein 1 | Solute carrier family 4 member 1
- Application:
- ELISA, Immunofluorescence, Western Blot
- translate.label.attr.clone:
- Q1/156
- Clonality:
- Monoclonal
- Extra Details:
- Band 3; also designated AE1; is an erythrocyte membrane glycoprotein that contributes to cell stuctural integrity and mediates exchange of chloride and bicarbonate across the phospholipid bilayer. The diverse functions of the approximately 900 amino acid protein are mediated by two distinct domains. The amino-terminal domain; also known as cdb3 for cytoplasmic domain of erthrocyte membrane band 3; acts as an attachment site for the erythrocyte skeleton by binding ankyrin. The carboxy-terminal; membrane-associated domain carries out exchange transport of anions. Degradation of band 3 can generate an aging antigen known as senescent cell antigen; or SCA; which is expressed on old cells and marks them for removal by the immune system. An isoform of band 3; which lacks the first 65 amino acids and does not bind ankryin; is expressed in kidney.
- Host:
- Mouse
- Immunogen:
- Human fetal liver cells.
- Isotype:
- IgG1
- Molecular Weight:
- 95kDa
- Research Area:
- Cardiovascular; Infectious Disease; Neuroscience
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=121264
