Interleukin-25 (IL-25) / IL-17E Antibody
Product Sizes
100 ug
£671.00
64806-MSM1-P1-100UG
About this Product
- SKU:
- 64806-MSM1-P1
- Additional Names:
- Interleukin-17E
- Application:
- Immunohistochemistry
- translate.label.attr.clone:
- IL25/625
- Clonality:
- Monoclonal
- Extra Details:
- Cytokines are small; soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. They exert their biological effects through the binding of membrane-bound receptors which; in turn; initiate signal transduction cascades and elicit physiological changes in their target cell. Interleukin-17 (IL-17) and its cognate receptor; IL-17R; are an example of such a cytokine receptor pair. Originally identified as a rodent cDNA termed CTLA8; IL-17 is capable of inducing the secretion of IL-6 and IL-8 and augmenting the expression of ICAM-1 in human fibroblast cultures. The IL-17 protein exhibits a striking degree of homology with the HSV-13 protein which mimics its function. The IL-17 receptor is a type I transmembrane protein 864 amino acids in length that is highly expressed in spleen and kidney.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human IL25 protein (exact sequence is proprietary)
- Isotype:
- IgG1
- Molecular Weight:
- 20kDa
- Research Area:
- Cardiovascular; Cytokine Signaling; Immunology
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Supplier:
- NeoBiotechnologies
- Type:
- Antibodies: Monoclonal Antibody
- Manufacturer's Data Sheet:https://www.neobiotechnologies.com/download-datasheet/?PID=121177
