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Antibodies

Interleukin-25 (IL-25) / IL-17E Antibody

Product Sizes
20 ug
£364.00
64806-MSM1-P0-20UG
About this Product
SKU:
64806-MSM1-P0
Additional Names:
Interleukin-17E
Application:
Immunohistochemistry
translate.label.attr.clone:
IL25/625
Clonality:
Monoclonal
Extra Details:
Cytokines are small; soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. They exert their biological effects through the binding of membrane-bound receptors which; in turn; initiate signal transduction cascades and elicit physiological changes in their target cell. Interleukin-17 (IL-17) and its cognate receptor; IL-17R; are an example of such a cytokine receptor pair. Originally identified as a rodent cDNA termed CTLA8; IL-17 is capable of inducing the secretion of IL-6 and IL-8 and augmenting the expression of ICAM-1 in human fibroblast cultures. The IL-17 protein exhibits a striking degree of homology with the HSV-13 protein which mimics its function. The IL-17 receptor is a type I transmembrane protein 864 amino acids in length that is highly expressed in spleen and kidney.
Host:
Mouse
Immunogen:
Recombinant fragment of human IL25 protein (exact sequence is proprietary)
Isotype:
IgG1
Molecular Weight:
20kDa
Research Area:
Cardiovascular; Cytokine Signaling; Immunology
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody