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Antibodies

Pulmonary Surfactant-Associated Protein D (SFTPD) Antibody

Product Sizes
20 ug
£364.00
6441-MSM3-P0-20UG
About this Product
SKU:
6441-MSM3-P0
Additional Names:
Collectin-7 | Lung surfactant protein D
Application:
Immunohistochemistry
translate.label.attr.clone:
SFTPD/4363
Clonality:
Monoclonal
Extra Details:
Pulmonary surfactant is primarily responsible for lowering the surface tension at the air-liquid interface in the alveoli; a process that is essential for normal respiration. Pulmonary surfactant is a mixture of phospholipids and proteins; including four distinct surfactant-associated proteins (SPs); SP-A; SP-B; SP-C; SP-D. SP-B and SP-C are predominantly hydrophobic proteins that associate with lipids to promote the absorption of surfactant phospholipids and to reduce the surface tension in the alveoli. SP-A and SP-D are large multimeric proteins belonging to the family of calcium-dependent lectins; designated Collectins; which contribute to the innate immune system. Both SP-A and SP-D have been shown to protect against microbial challenge through binding to the lipid components of the bacterial cell wall and facilitating the rapid removal of microbials.
Host:
Mouse
Immunogen:
Recombinant fragment (around aa241-336) ofhuman SFTPD protein (exact sequence is proprietary)
Isotype:
IgG2c
Molecular Weight:
43kDa
Research Area:
Cardiovascular; Immunology; Infectious Disease
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody