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Antibodies

SCXA Antibody

Product Sizes
100 ug
£671.00
642658-MSM2-P1-100UG
About this Product
SKU:
642658-MSM2-P1
Additional Names:
Class A basic helix-loop-helix protein 41 | Class A basic helix-loop-helix protein 48
Application:
Flow Cytometry, Immunofluorescence
translate.label.attr.clone:
PCRP-SCXA-2D11
Clonality:
Monoclonal
Extra Details:
Transcription factors are proteins that bind DNA adjacent to genes and control the production of mRNA transcripts. Scleraxis (basic helix-loop-helix transcription factor scleraxis) is a 201 amino acid protein that dimerizes with another bHLH protein to initiate transcription. Scleraxis is known to play a role in formation of mesoderm and somite-derived chondrogenic lineages. Scleraxis localizes to the nucleus and contains one bHLH domain. bHLH transcription factors; in general; function in cellular differentiation; proliferation; and oncogene regulation. The gene encoding Scleraxis maps to human chromosome 8; which consists of nearly 146 million base pairs; houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia; bipolar disorder; Trisomy 8; Pfeiffer syndrome; congenital hypothyroidism; Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.
Host:
Mouse
Immunogen:
Recombinant full-length human SCXA protein
Isotype:
IgG2a
Molecular Weight:
22kDa
Shipping Conditions:
Blue Ice
Storage Conditions:
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplier:
NeoBiotechnologies
Type:
Antibodies: Monoclonal Antibody